Menoufia Medical Journal

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 29  |  Issue : 2  |  Page : 389--392

A study on the effect of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melisma


Mohamed A Basha, Rania M Azmy, Mai M Farag 
 Department of Physiology, Faculty of Medicine, Menoufia University, Menufia, Egypt

Correspondence Address:
Mai M Farag
Department of Dermatology, Faculty of Medicine, Mansoura University, Al Azher Street, Bani Ebaied-Mansoura Governorate, 35117
Egypt

Objective: The aim of the study was to assess the efficacy of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melasma. Materials and methods: From January 2013 to June 2013, 40 female patients with melasma and 20 age-matched and sex-matched healthy individuals as the control group were included. Estrogen and progesterone were measured using IMMULITE 2000. Results: Concerning the serum estrogen and progesterone levels, the patients showed a statistically significant increase in progesterone levels with a mean value of 3.65 ± 13.11 when compared with the controls with a mean value of 3.63 ± 2.64. Conclusion: Increase in serum progesterone supports the role of pregnancy in melasma.


How to cite this article:
Basha MA, Azmy RM, Farag MM. A study on the effect of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melisma.Menoufia Med J 2016;29:389-392


How to cite this URL:
Basha MA, Azmy RM, Farag MM. A study on the effect of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melisma. Menoufia Med J [serial online] 2016 [cited 2024 Mar 28 ];29:389-392
Available from: http://www.mmj.eg.net/article.asp?issn=1110-2098;year=2016;volume=29;issue=2;spage=389;epage=392;aulast=Basha;type=0