TY - JOUR
A1 - Hassanein, Shaimaa
A1 - Mohamed, Hala
A1 - Mostafa, Aya
A1 - Gomaa, Manal
T1 - In-phase and out-of-phase MRI: a quantitative method for assessment of nonalcoholic fatty liver disease
Y1 - 2020/7/1
JF - Menoufia Medical Journal
JO - Menoufia Med J
SP - 987
EP - 992
VL - 33
IS - 3
UR - http://www.mmj.eg.net/article.asp?issn=1110-2098;year=2020;volume=33;issue=3;spage=987;epage=992;aulast=Hassanein
DO - 10.4103/mmj.mmj_79_19
N2 -
Objective
The objective of this study was to assess the efficacy of MRI in-phase and out-of-phase (IPOP) technique in the diagnosis of nonalcoholic fatty liver disease (NAFLD).
Background
NAFLD is raising great concern nowadays due to its prevalence. It was routinely diagnosed by liver biopsy, which is a highly invasive procedure; hence, the need for a noninvasive method for diagnosis was required. MRI IPOP technique was introduced to fulfill this role.
Patients and methods
This prospective study was carried out during the period spanning from July 2016 to December 2017; 50 asymptomatic patients with clinical diagnosis of NAFLD and diffuse hyperechogenicity of the liver by ultrasound underwent MRI of the liver with IPOP technique. Manually placed region of interest and two equations, namely F1 and F2, for determination of the grades of steatosis were used.
Results
The first equation (F1) revealed one patient (male individual) to have minimal steatosis, 24 patients (17 female individuals, seven male individuals) to have mild steatosis, 22 patients (15 female individuals, seven male individuals) to have moderate steatosis and three patients (two female individuals, one male individual) to have marked steatosis, whereas the second equation (F2) revealed one patient (male individual) to have minimal steatosis, 20 patients (13 female individuals, seven male individuals) to have mild steatosis, 26 patients (19 female individuals, seven male individuals) to have moderate steatosis and three patients (two female individuals, one male individual) to have marked steatosis.
Conclusion
Liver MRI with IPOP technique can be used rapidly and quantitatively to estimate the liver fat content in patients with NAFLD.
ER -