ORIGINAL ARTICLE |
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Year : 2022 | Volume
: 35
| Issue : 4 | Page : 1903-1909 |
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Comparison between digital breast tomosynthesis plus mammography and mammography alone for breast cancer detection
Al-Sayed A Al-Sayed1, Yasmin H Hemeda1, Omar F AlOraby2
1 Department of Radiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt 2 Department of Radiology, Al Haram Specialized Hospital, Giza, Egypt
Correspondence Address:
Omar F AlOraby Quesna, Menoufia Egypt
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/mmj.mmj_286_22
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Objective
To compare cancer detection rates of digital breast tomosynthesis (DBT) plus conventional digital mammography (DM) with those of conventional DM alone.
Background
DBT is a recent evolution of full-field digital mammography (FFDM) involving quasi-three-dimensional (3D) transformation of breast images.
Patients and methods
The study was conducted on 35 females who were eligible for examination by 3D DBT, who were referred to the National Cancer Institute – Female Imaging Unit in the duration from May 2020 to May 2021. Full history taking and complete clinical examination were performed on all patients. All patients were examined by FFDM and wide-angle 3D DBT.
Results
The diagnostic performance of combined DBT + DM outcome, when compared with the results of histopathological assessment of lesions biopsies, was as such: sensitivity (92.6%), specificity (87.5%), positive predictive value (96.2%), negative predictive value (77.8%), and accuracy (91.4%), which indicates statistically significant agreement between the two tests as their yielded weighted κ value is 0.767, which indicates a substantial agreement with a highly significant P value. However, it is only, in case of DM alone, a weighted κ value of 0.449 indicates a moderate agreement with a significant P value.
Conclusion
DBT showed better detection of subtle spiculations and enhanced ability of multifocality identification due to its ability to overcome tissue overlapping unlike DM alone.
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