Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2022  |  Volume : 35  |  Issue : 3  |  Page : 1099-1104

Assessment of the efficacy and safety of platelet-poor plasma gel as autologous dermal filler for facial rejuvenation


1 Department of Dermatology, Andrology and STDs, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Correspondence Address:
Amira F M. El-Sandebisi
Menouf City, Menoufia
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_137_22

Rights and Permissions

Objective This study was designed to evaluate the clinical efficacy and safety of plasma gel as a dermal-filler injection for facial rejuvenation. Background The popularity of dermal fillers has grown rapidly in the last few years for facial rejuvenation. Plasma gel is an autologous gelatinous material that is prepared from the patient's own platelet-poor plasma (PPP). Plasma gel had gained popularity in plastic surgery, orthopedic surgery, oral surgery, and various other fields. Patients and methods A cross-sectional study was carried out on 200 females more than 40 years presented with facial aging. They were divided into two main groups: group A included satisfied females with different types and grades of facial wrinkles (150 patients), and group B included unsatisfied females with different types and grades of facial wrinkles (50 patients) selected from the Outpatient Clinic of Dermatology and Venereology Department, Menoufia General and Menoufia University Hospitals, after taking a written informed consent. They were assessed clinically before treatment sessions and at the end of the follow-up period. Results All patients showed immediate significant clinical improvement after plasma-gel injection that maintained till the end of the follow-up period. This finding was confirmed by significant reduction in the mean values of Wrinkle Severity Rating Scale (WSRS) and Tear Trough Rating Scale (TTRS). Patient's satisfaction was significantly correlated with WSRS, TTRS, and absence of complication (r: 0.57, 0.63, and –0.283, respectively). The cutoff points of TTRS score and WSRS for best satisfaction were 1.2 and 0.98, respectively, with high area under the curve (0.91, 0.89, respectively). Conclusion PPP-gel injection technique is a safe treatment method for all skin types. Autologous PPP-gel injection seems to be cost-effective, safe, well-tolerated, and minimally invasive technique producing significant aesthetic correction of facial wrinkles and tear-trough deformity.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1035    
    Printed36    
    Emailed0    
    PDF Downloaded105    
    Comments [Add]    

Recommend this journal