Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2022  |  Volume : 35  |  Issue : 1  |  Page : 8-13

Incidence of myocardial infarction with nonobstructive coronary arteries in patients with acute coronary syndrome


1 Department of Cardiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Cardiology, National Heart Institute, Cairo, Egypt
3 Department of Cardiology, Ministry of Health, National Heart Institute, Cairo, Egypt

Correspondence Address:
Ahmed M Abdel Aal
43 Studiomasr Street, Al Haram, Al Giza
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_331_20

Rights and Permissions

Objective To estimate the incidence of myocardial infarction with nonobstructive coronary arteries (MINOCA) among Egyptian cases with acute myocardial infarction (AMI) and to evaluate the role of neutrophilic elastase in AMI cases. Background Previous research studies have declared that MINOCA is a syndrome with angiographic normal or near-normal coronary arteries but had evidence of MI clinically, which has many causes. Patients and methods To reach the goal of this research, a group study was designed. A total of 627 cases admitted at Cardiology Department of Faculty of Medicine Menoufia University and National Heart Institute in the period from February 2019 to July 2019 were included. Cases were divided into two groups: group 1 included AMI cases with obstructive coronary artery disease group, and group 2 included AMI cases with nonobstructive coronary artery disease (MINOCA group). All cases were subjected to (a) full history taking; (b) clinical examination; (c) laboratory investigations, such as serum HbA1C, cardiac enzymes (total creatine kinase, creatine kinase-myocardial band, and troponin), and serum neutrophil elastase; and (d) other investigations, including ECG and coronary angioplasty. Results There were 627 acute coronary syndrome cases, and 49 cases were diagnosed as MINOCA. Regarding the risk factors, diabetes mellitus and smoking showed a significant difference in-between both studied groups (P = 0.038 and 0.014, respectively). Conclusion Our study concluded that ~7.8% of the Egyptian cases that presented with AMI for primary percutaneous coronary intervention have MINOCA. High serum neutrophilic elastase concentration is a sensitive marker, suggesting the existence of complex atheromatous plaques in AMI cases.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed214    
    Printed14    
    Emailed0    
    PDF Downloaded64    
    Comments [Add]    

Recommend this journal