ORIGINAL ARTICLE |
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Year : 2021 | Volume
: 34
| Issue : 2 | Page : 440-445 |
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Evaluation of serum vaspin levels with the severity of coronary artery disease
Laila M Montaser1, Dalia H Abou-Elela1, Rehab I Yasin2, Safwa F El Shorbagy1
1 Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Menoufia, Egypt 2 Department of Cardiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Correspondence Address:
Safwa F El Shorbagy Elbrahymia, Kotour, Gharbia Governorate Egypt
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/mmj.mmj_307_19
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Objective
The objective of this study was to evaluate serum visceral adipose tissue-derived serpin (vaspin) level with the severity of coronary artery disease (CAD).
Background
There is controversy between the researchers on the subject of serum vaspin concentration in CAD.
Patients and methods
Twenty control and 68 CAD patients were enrolled in this study. Vaspin was detected by enzyme-linked immunosorbent assay method.
Results
Serum levels of vaspin were significantly low in patients with CAD compared with healthy controls and low vaspin concentrations were correlated with CAD severity.
Conclusions
Decreased serum vaspin levels were observed in the existence and severity of CAD in patients assessed by coronary angiography.
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