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Year : 2021  |  Volume : 34  |  Issue : 1  |  Page : 71-75

Helicobacter pylori infection in the palm and sole of psoriatic patients

1 Department of Dermatology, Andrology and STDs, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
3 Dermatology, Andrology and STDs, Menoufia Health Sector, Menoufia, Egypt

Correspondence Address:
Asmaa M Abousaeida
Shiben El-Kom, Menoufia Governorate
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mmj.mmj_246_19

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Objective To clarify the role of Helicobacter pylori infection in psoriatic patients with palm and sole affection Background Psoriasis is a chronic inflammatory disease that affects 2–3% of the population worldwide. H. pylori infection has been implicated in the pathogenesis of various skin diseases. Patients and methods This case–control study was conducted on 40 patients with psoriasis vulgaris and 40 age-matched and sex-matched healthy individuals. All patients were subjected to history taking and complete medical examination. Serum levels of anti-H. pylori immunoglobulin G were measured by enzyme-linked immunosorbent assay technique. Serum levels of anti-H. pylori immunoglobulin G were statistically analyzed in relation to psoriasis area and severity index score. Results H. pylori infection was more prevalent among patients who did not manifest palm and sole affection. However, 50% of palm-affected and sole-affected patients were positive for H. pylori infection (P = 0.02). Conclusion H. pylori may play a significant role in the development of palmoplantar psoriasis and may provide important clues to assist in the development of new therapeutic strategies for palmoplantar psoriatic patients through its eradication.

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