Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2021  |  Volume : 34  |  Issue : 1  |  Page : 129-134

Effect of the mean platelet volume/platelet count ratio on arteriovenous fistula function in chronic hemodialysis patients


1 Department of Internal Medicine, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Resident of Internal Medicine at Ministry of Health, Shebein El Koum Teaching Hospital, Menoufia, Egypt

Correspondence Address:
Manar A. H. Tahoon
Shebin Elkom, Menoufia
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_230_19

Rights and Permissions

Objective The aim was to study the effect of increased mean platelet volume/platelet count (MPV/PL count) on arteriovenous fistula (AVF) function in chronic hemodialysis (HD) patients. Background Vascular access failure substantially contributes to morbidity and hospitalization in HD patients. Patients and methods A case–control study was conducted on 50 HD patients on regular HD for more than 6 months in Shebin El-Koom Teaching Hospital, Menoufia, Egypt. The patients were divided into two groups: 25 patients with functioning AVF as group 1 and 25 patients with nonfunctioning AVF as group 2. Patients were subjected to full history taking, clinical examination, laboratory workup, and radiology by Duplex ultrasound. Results There was no significant effect of age, sex, BMI, diabetes mellitus, hypertension, smoking, or type of anastomosis on AVF in HD patients. There was a significant effect of intradialysis hypotension on AVF in HD patients. There was a highly significant effect of fistula function on Kt/V in HD patients. There was a highly significant increase of MPV/PL count ratio in HD patients with failure of AVF. MPV/PL count at a cut-off level of 53.7 can accurately predict failure of AVF in the studied HD patients with 100% sensitivity and 84% specificity. Conclusion Assessment of MPV/PC ratio could adequately predict the failure of the function of AVF in the studied patients.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed206    
    Printed0    
    Emailed0    
    PDF Downloaded34    
    Comments [Add]    

Recommend this journal