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Year : 2020  |  Volume : 33  |  Issue : 3  |  Page : 830-834

Pattern of lipid profile in pregnancy and its impact on the gestational course

1 Department of Cardiology, Faculty of Medicine, Menoufia University, Menoufia Governorate, Egypt
2 Department of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Menoufia Governorate, Egypt
3 Department of Cardiology at Dar Alfouad Hospital, Giza, Egypt
4 Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo Governorate, Egypt

Correspondence Address:
Gehad Gamal
377 L Ahram Gardens, 6th October City, Cairo Governorate
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mmj.mmj_327_18

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Objective The aim was to screen lipid profile in pregnancy and assess the association between second trimester maternal lipid profile and gestational outcome. Background Major changes in lipid profile occur during normal pregnancy and significant association with gestational complications could be confirmed. Materials and methods This cohort study included 94 women with maternal lipid profile assessed during the second trimester (16–18 weeks). Serial antenatal visits were conducted to record the development of maternal gestational hypertension (GH), preeclampsia (PE), gestational diabetes mellitus (GDM), and low birth weight. Results Lipid profile components in pregnancy are higher than normal references. Meanwhile, GH was the most common complication in the study affecting 13 (13.8%) patients followed by PE in eight (8.5%) patients, GDM in seven (7.4%) patients, and lastly low birth weight in four (4.3%) neonates. A positive association between second trimester lipid profile components and GH, PE, and GDM was found. Conclusion Lipid profile during the second trimester should be done routinely especially in patients with hypertensive disorders and GDM.

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