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Year : 2020  |  Volume : 33  |  Issue : 3  |  Page : 1050-1054

Lipid profile in cases of lichen planus

1 Department of Dermatology, Andrology and STIs, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Medical Biology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
3 Department of Dermatology, Shebi El-Kom Dermatology and Leprosy Hospital, Menoufia, Egypt

Correspondence Address:
Eman M. H Abd El Hamid El Khateeb
Department of Dermatology, Shebi El.Kom Dermatology and Leprosy Hospital, Menoufia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mmj.mmj_92_19

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Objective The aim of this work is to measure serum lipid profile in lichen planus) LP (cases for assessment of possible myocardial ischemia in these cases. Background LP is a chronic inflammatory disease that affects the skin and mucous membranes. It occurs mostly in individuals older than 45 years, and it is more common among women. Lipids are a broad group of naturally occurring molecules. High levels of triglycerides in the blood stream have been linked to atherosclerosis and, by extension, the risk of heart disease and stroke. Atherogenic lipid profile leads to atherosclerosis, which may be complicated by cerebral stroke, myocardial infarction, and/or peripheral vascular disease. Patients and methods This case–control study was carried out on 20 nonobese cases with LP as patient group and 20 age-matched, sex-matched, and BMI-matched healthy participants as a control group. All participants were subjected to full history taking, clinical examination, and laboratory investigations (blood lipid profile). Results Our results showed no significant difference between cases and controls regarding age and sex. There was no significant difference between cases and controls regarding blood pressure and BMI. There was a highly significant difference between case and control groups regarding serum cholesterol, high-density lipoprotein, and low-density lipoprotein. Conclusion Serum cholesterol, high-density lipoprotein, and low-density lipoprotein may be better predictors of cardiovascular risk in patients with LP.

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