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Year : 2018  |  Volume : 31  |  Issue : 1  |  Page : 98-101

The role of tranexamicacidin improving quality of pediatric tonsillectomy: a double-blinded randomizedcontrolledstudy

1 Department of Otolaryngology-Head and Neck Surgery, Kaferelsheikh University, Kafr El-Sheikh, Egypt
2 Department of Anesthesia and ICU, Tanta University, Tanta, Egypt

Correspondence Address:
Ahmed S Elgebaly
Department of Anesthesia and ICU, Faculty of Medicine, Tanta University, Tanta 31511
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mmj.mmj_377_17

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Design This was a prospective, double-blinded, randomized controlled study. Patients and methods The present study included 100patientsrandomized into two groups: groupI included patients who did not receive tranexamic acid and groupII included patients who were given tranexamic acid after induction intravenously as 15mg/kg over10min. Results In groupI, the mean number and weight of gauze used during surgery were 5.1+1.30 pieces and 72±6.334ml, respectively, and in groupII, they were 1.9±0.35 pieces and 41±8.221ml, respectively(P<0.001). In groupI, the mean amount of blood in suction bag was 200±52.36ml, whereas it was 50±10.36ml in groupII(P<0.001). The difference between both groups regarding the number of gauze, weight, and the amount of blood in suction bag was highly significant(P<0.001). Conclusion The present study showed that 15mg/kg of tranexamic acid can reduce intraoperative blood loss in a highly significant manner in children undergoing tonsillectomy and in keeping stability in hemoglobin, hematocrit levels, heart rate, mean arterial blood pressure, and respiratory rate postoperatively.

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