Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2016  |  Volume : 29  |  Issue : 4  |  Page : 846-854

Study of bacteremia in diabetic patients

1 Department of Medical Microbiology and Immunology, National Liver Institute, Menoufia, Egypt
2 Department of Medical Microbiology and Immunology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Correspondence Address:
Eman H Hassan Salem
Shebien El Kom, Menoufia, 32511
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1110-2098.202512

Rights and Permissions

Objectives The objective of this study was to assess the rate of bacteremia, the most common bacteria, its antibiotic sensitivity pattern, and the role of immunity in its occurrence in diabetic patients. Background Bacteremia constitutes the most severe end of the spectrum of frequent community-acquired infections, and the prevalence, and thus disease burden, of bacteremia has increased during the past decades analogous with diabetes. Materials and methods A total of 160 individuals (93 male and 67 female with a mean age of 48.0 ± 9.7 years) were divided into the following groups: 60 diabetics with infections (group I), 70 nondiabetics with infections (group II), and 30 apparently healthy persons as controls; the studied groups were subjected to full medical history, clinical examination, and bacteriological examination of blood, antibiotic sensitivity pattern for the isolated microorganisms, measurement of serum IgM, IgG by radioimmunodiffusion, and T lymphocyte level by flow cytometry. Results The rate of bacteremia in group I was significantly higher than in group II (P = 0.007), the level of IgM and CD3 in group I was significantly higher than in group II (P = 0.003), and total leucocytic count in group I was significantly higher than in group II (P < 0.001). Staphylococcus aureus was the most common organism isolated form blood of diabetic patients, and 90.9% of them were sensitive to amikacin, followed by imipenem, vancomycin, and ceftriaxone (81.8%). Conclusion Diabetes increases the risk of exposure to bacteremia and affects the immune response to bacteremia.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded137    
    Comments [Add]    

Recommend this journal