| ORIGINAL ARTICLE |
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| Year : 2016 | Volume
: 29
| Issue : 2 | Page : 389-392 |
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A study on the effect of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melisma
Mohamed A Basha, Rania M Azmy, Mai M Farag
Department of Physiology, Faculty of Medicine, Menoufia University, Menufia, Egypt
Correspondence Address:
Mai M Farag
Department of Dermatology, Faculty of Medicine, Mansoura University, Al Azher Street, Bani Ebaied-Mansoura Governorate, 35117
Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1110-2098.192411
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Objective:
The aim of the study was to assess the efficacy of estrogen, progesterone, and their cutaneous receptors in the pathogenesis of melasma.
Materials and methods:
From January 2013 to June 2013, 40 female patients with melasma and 20 age-matched and sex-matched healthy individuals as the control group were included. Estrogen and progesterone were measured using IMMULITE 2000.
Results:
Concerning the serum estrogen and progesterone levels, the patients showed a statistically significant increase in progesterone levels with a mean value of 3.65 ± 13.11 when compared with the controls with a mean value of 3.63 ± 2.64.
Conclusion:
Increase in serum progesterone supports the role of pregnancy in melasma. |
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