ORIGINAL ARTICLE |
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Year : 2016 | Volume
: 29
| Issue : 2 | Page : 285-290 |
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Transarterial ethanol ablation of hepatocellular carcinoma with lipiodol–ethanol mixture
Adel M El Wakeel1, Mohammed S El Warraky1, Tarek F Abd Ella2, May S El Safty3
1 Department of Diagnostic Radiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt 2 Department of Diagnostic Radiology and Interventional, National Liver Institution, Menoufia University, Menoufia, Egypt 3 Department of Diagnostic Radiology, El Menashowy Hospital, Egypt
Correspondence Address:
May S El Safty Omar Ibn Abd El Aziz, Tanta, 31511 Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1110-2098.192426
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Objective:
The aim of the study was to determine the safety and effectiveness of transarterial embolization ablation (TEA) of hepatocellular carcinoma (HCC) with a lipiodol–ethanol mixture.
Background:
TEA is a new treatment strategy for HCC, and some researchers have reported its effectiveness in HCC.
Patients and methods:
This study was a prospective cohort study conducted at the National Liver Institute and Faculty of Medicine, Menoufia University, and included 40 patients having unresectable HCCs. At 3 and 6 months after TEA, triphasic computed tomography was performed, and tumor responses were assessed using a modified version of Response Evaluation Criteria in Solid Tumor (mRECIST).
Results:
Every case was treated. At 3 and 6 months after embolization, contrast computed tomography showed no enhancing lesions.
a-Fetoprotein levels were significantly reduced (12.18 ± 15.67) at 6 months after treatment. The partial and complete responses of tumors were 12.5 and 87.5%, respectively, 6 months after treatment. The overall survival rate was 90%.
Conclusion:
TEA is an effective therapy for patients with unresectable HCC. |
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