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Figure 4: Photomicrographs of glial fibrillary acidic protein (GFAP)-stained sections (GFAP ×400) of the hippocampus: (a) An adult rat aged 8 months showing a few astrocytes with small size, short branches, and faint brown immunoreaction (black arrows). (b) A rat aged 22 months showing an apparent increase in the number and size of astrocytes with intense brown positive immunoreaction in the cytoplasm and the processes of these astrocytes. (c) A rat aged 26 months showing an increase in the number of astrocytes with intense brown positive immunoreaction for GFAP in the cytoplasm and the processes of these astrocytes. Notice: increased in size with long processes (black arrows). |
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