Figure 4: A photomicrograph showing the immunohistochemical staining of antiglial fibrillary acidic protein (GFAP) expression of the cerebral cortex in different groups of rat after 7 days. (a) Control group (b) group II showing strong positive immunoreactivity. Extensive overlapping and interdigitations of processes of astrocytes (arrow head) were noted. (c) Group III showing less astrocytic density with moderately reactive astrocyte processes. (d) Group IV showing GFAP reaction nearly similar to the control group (GFAP ×400).