ORIGINAL ARTICLE
Year : 2019 | Volume
: 32 | Issue : 1 | Page : 67--73
Effect of transcranial magnetic stimulation in patients with Parkinson disease
Wafik M El-Shiekh1, Rasha A El-Kabbany1, Aktham I El-Emam1, Ibrahim E Al-Ahmar1, Mohamed A Eltantawi2 1 Department of Neuropsychiatry, Faculty of Medicine, Menoufia University, Menoufia, Egypt 2 Department of Neurology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Correspondence Address:
Mohamed A Eltantawi Mansoura, Dakahlia Egypt
Objective
The aim was to study the possible effect of repetitive transcranial magnetic stimulation (rTMS) as a treatment option in patients with Parkinson disease (PD) whose conditions become complicated owing to either progression of the disease or adverse effects of the drugs.
Background
PD is the second most common neurodegenerative disease. Drug-related motor complications, for example, dyskinesias, or nonmotor complications, for example, depression, happen in the later stages of the disease, even among those on levodopa therapy. Transcranial magnetic stimulation (TMS) has been used in a wide range of diseases associated with motor dysfunction. rTMS has shown good improvement of clinical condition among patients with PD.
Patients and methods
The study is a prospective case–controlled clinical trial. A total of 40 patients with PD were included in the study and divided into two groups: group I underwent active rTMS (20 patients) and group II underwent sham stimulation (20 patients).
Results
Overall, 40 patients with complicated PD completed the study (group I included 20 patients and group II also had 20 patients). There was no statistically significant difference between the groups regarding age, sex, duration of illness, or stage of the disease (P > 0.05). After rTMS application, group I showed significant results regarding the stage of the disease (P < 0.05) and showed highly significant results regarding the severity of motor affection and complications (P < 0.001), whereas group II showed no significance (P > 0.05).
Conclusion
rTMS maybe a good addition to the management of motor symptoms and complications in complicated PD.
How to cite this article:
El-Shiekh WM, El-Kabbany RA, El-Emam AI, Al-Ahmar IE, Eltantawi MA. Effect of transcranial magnetic stimulation in patients with Parkinson disease.Menoufia Med J 2019;32:67-73
|
How to cite this URL:
El-Shiekh WM, El-Kabbany RA, El-Emam AI, Al-Ahmar IE, Eltantawi MA. Effect of transcranial magnetic stimulation in patients with Parkinson disease. Menoufia Med J [serial online] 2019 [cited 2024 Mar 29 ];32:67-73
Available from: http://www.mmj.eg.net/article.asp?issn=1110-2098;year=2019;volume=32;issue=1;spage=67;epage=73;aulast=El-Shiekh;type=0 |
|
|