Menoufia Medical Journal

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 31  |  Issue : 1  |  Page : 98--101

The role of tranexamic acid in improving quality of pediatric tonsillectomy: a double-blinded randomized controlled study


Saad D Elzayat1, Ahmed S Elgebaly2 
1 Department of Otolaryngology-Head and Neck Surgery, Kaferelsheikh University, Kafr El-Sheikh, Egypt
2 Department of Anesthesia and ICU, Tanta University, Tanta, Egypt

Correspondence Address:
Ahmed S Elgebaly
Department of Anesthesia and ICU, Faculty of Medicine, Tanta University, Tanta 31511
Egypt

Design This was a prospective, double-blinded, randomized controlled study. Patients and methods The present study included 100 patients randomized into two groups: group I included patients who did not receive tranexamic acid and group II included patients who were given tranexamic acid after induction intravenously as 15 mg/kg over 10 min. Results In group I, the mean number and weight of gauze used during surgery were 5.1 + 1.30 pieces and 72 ± 6.334 ml, respectively, and in group II, they were 1.9 ± 0.35 pieces and 41 ± 8.221 ml, respectively (P < 0.001). In group I, the mean amount of blood in suction bag was 200 ± 52.36 ml, whereas it was 50 ± 10.36 ml in group II (P < 0.001). The difference between both groups regarding the number of gauze, weight, and the amount of blood in suction bag was highly significant (P < 0.001). Conclusion The present study showed that 15 mg/kg of tranexamic acid can reduce intraoperative blood loss in a highly significant manner in children undergoing tonsillectomy and in keeping stability in hemoglobin, hematocrit levels, heart rate, mean arterial blood pressure, and respiratory rate postoperatively.


How to cite this article:
Elzayat SD, Elgebaly AS. The role of tranexamic acid in improving quality of pediatric tonsillectomy: a double-blinded randomized controlled study.Menoufia Med J 2018;31:98-101


How to cite this URL:
Elzayat SD, Elgebaly AS. The role of tranexamic acid in improving quality of pediatric tonsillectomy: a double-blinded randomized controlled study. Menoufia Med J [serial online] 2018 [cited 2020 Apr 2 ];31:98-101
Available from: http://www.mmj.eg.net/article.asp?issn=1110-2098;year=2018;volume=31;issue=1;spage=98;epage=101;aulast=Elzayat;type=0