Menoufia Medical Journal

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 30  |  Issue : 3  |  Page : 880--886

Reticulated platelets in acute coronary syndrome patients


Khaled A Khalifa1, Mohamed A Helwa1, Asmaa M Mohammed Mousa2 
1 Clinical Pathology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Shebin El-Kom Teaching Hospital, Menoufia, Egypt

Correspondence Address:
Asmaa M Mohammed Mousa
Shebin El-Kom, Menoufia, 32511
Egypt

Objective The aim of this study was to evaluate reticulated platelets (RP) as a predicting factor of the outcome in acute coronary syndrome (ACS) patients. Background ACS is due to rupture of an arterial plaque. RPs are newly formed platelets with a greater mass, residual amount of RNA, and an increased prothrombotic potential compared with mature platelets. In this study, the RPs were investigated as participating factors in the pathogenesis of ACS. Patients and methods A total of 50 patients with ACS [33 acute myocardial infarction (AMI) and 17 unstable angina] and 15 clinically healthy individuals as controls were investigated for RPs by means of flowcytometry analysis. Results RPs were highly significantly increased in AMI than in unstable angina and controls. Conclusion High levels of RPs are found in ACS patients and it can be used as a predictor for adverse outcome. Moreover, it can participate in the development of AMI due to its high thrombogenic potential.


How to cite this article:
Khalifa KA, Helwa MA, Mohammed Mousa AM. Reticulated platelets in acute coronary syndrome patients.Menoufia Med J 2017;30:880-886


How to cite this URL:
Khalifa KA, Helwa MA, Mohammed Mousa AM. Reticulated platelets in acute coronary syndrome patients. Menoufia Med J [serial online] 2017 [cited 2024 Mar 29 ];30:880-886
Available from: http://www.mmj.eg.net/article.asp?issn=1110-2098;year=2017;volume=30;issue=3;spage=880;epage=886;aulast=Khalifa;type=0