Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2019  |  Volume : 32  |  Issue : 1  |  Page : 67-73

Effect of transcranial magnetic stimulation in patients with Parkinson disease


1 Department of Neuropsychiatry, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Neurology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Correspondence Address:
Mohamed A Eltantawi
Mansoura, Dakahlia
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_261_17

Rights and Permissions

Objective The aim was to study the possible effect of repetitive transcranial magnetic stimulation (rTMS) as a treatment option in patients with Parkinson disease (PD) whose conditions become complicated owing to either progression of the disease or adverse effects of the drugs. Background PD is the second most common neurodegenerative disease. Drug-related motor complications, for example, dyskinesias, or nonmotor complications, for example, depression, happen in the later stages of the disease, even among those on levodopa therapy. Transcranial magnetic stimulation (TMS) has been used in a wide range of diseases associated with motor dysfunction. rTMS has shown good improvement of clinical condition among patients with PD. Patients and methods The study is a prospective case–controlled clinical trial. A total of 40 patients with PD were included in the study and divided into two groups: group I underwent active rTMS (20 patients) and group II underwent sham stimulation (20 patients). Results Overall, 40 patients with complicated PD completed the study (group I included 20 patients and group II also had 20 patients). There was no statistically significant difference between the groups regarding age, sex, duration of illness, or stage of the disease (P > 0.05). After rTMS application, group I showed significant results regarding the stage of the disease (P < 0.05) and showed highly significant results regarding the severity of motor affection and complications (P < 0.001), whereas group II showed no significance (P > 0.05). Conclusion rTMS maybe a good addition to the management of motor symptoms and complications in complicated PD.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed97    
    Printed2    
    Emailed0    
    PDF Downloaded7    
    Comments [Add]    

Recommend this journal