Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2018  |  Volume : 31  |  Issue : 1  |  Page : 250-253

Assessment of serum iron and zinc levels in rhinoscleroma patients


Department of Otorhinolaryngology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Correspondence Address:
Sohair R Abo Shady
Department of Otorhinolaryngology, Faculty of Medicine, Menoufia University, Menoufia
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.234226

Rights and Permissions

Objective This study aimed to determine the relation of serum levels of iron and zinc trace elements during the course of rhinoscleroma and stage of disease. Background Several risk factors have been associated with rhinoscleroma such as poor hygiene and nutritional deficiencies. Therefore, iron and zinc deficiencies may be predisposing factors to the disease or may be a sequel of the disease as they are essential for cell-mediated immunity, which affects the pathophysiology of the disease. Patients and methods Seventy-eight participants(39cases diagnosed with rhinoscleroma and 39 controls) were enrolled into the study. Patients were subjected to nasal biopsy and a histopathological examination to diagnose rhinoscleroma, and laboratory assessments of serum levels of iron and zinc to determine the changes in serum levels of iron and zinc in patients diagnosed with rhinoscleroma. Results There was a significant decrease in the serum level of iron in the case group compared with the control group(P=0.00) and a significant decrease in the serum level of zinc in the case group compared with the control group(P=0.00). Also, there was a significant decrease in the serum levels of iron and zinc in the late-stage cases. Conclusion Serum levels of iron and zinc were significantly lower in patients diagnosed with rhinoscleroma than controls, reflecting the crucial role of iron and zinc in cell-mediated immunity in such patients.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed295    
    Printed7    
    Emailed0    
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal