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ORIGINAL ARTICLE
Year : 2018  |  Volume : 31  |  Issue : 1  |  Page : 225-228

Serum albumin and base deficit as prognostic factors for mortality in major burn patients


1 Department of PlasticSurgery, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of General Surgery, Faculty of Medicine, Menoufia University, Menoufia, Egypt
3 Department of Chest, Faculty of Medicine, Menoufia University, Menoufia, Egypt
4 Department of Plastic Surgery, Ahmed Maher Teaching Hospital, Cairo, Egypt

Correspondence Address:
Mohamed M Mansour
Zagazig, Sharquia
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mmj.mmj_714_16

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Objective The objective of this study was to assess serum albumin and base deficit as prognostic factors for mortality in major burn patients. Background Hypoalbuminemia is a common clinical deficiency in burn patients and is associated with complications related to increased extravascular fluid, including edema, abnormal healing, and susceptibility to sepsis. Base deficit is routinely calculated on blood gas analysis, and it provides the best estimate of the degree of tissue anoxia and shock at the whole body level, particularly in hemorrhagic shock. Arising base deficit indicates increasing metabolic acidosis, and may stratify mortality in patients after major trauma. Some prognostic scales do not include biochemical parameters, whereas others consider them together with comorbidities. The purpose of this study was to determine whether serum albumin and base deficit can predict mortality in burn patients. Patients and methods This study included 42patients. All patients were admitted to the burn ICU at Menoufia University Hospital. Serum albumin and base deficit were estimated in patients at admission, after 3days, and after 1week. Results The mean of serum albumin on admission was 3.33±0.44g/dl, after 3days it was 2.85±0.54g/dl, and after 1week it was 2.46±0.67g/dl, and the mean of base deficit was 5.75±2.40, 5.24±2.05, and 5.45±2.76, respectively. These results were significant(P<0.001). Conclusion Statistically, serum albumin and base deficit can be used as prognostic factors for mortality, and colloid therapy should be continued for the first week, not only for the first 3days.


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