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ORIGINAL ARTICLE
Year : 2017  |  Volume : 30  |  Issue : 2  |  Page : 517-524

Comparisonbetweencorneal biomechanics and HbA1c levels in healthy individuals and type2 diabetic patients


1 Department of Ophthalmology, Menoufia University, Menoufia, Egypt
2 Research Institute of Ophthalmology, Giza, Egypt

Correspondence Address:
Mahmoud E El Bahnasy
ElBahnasy, El-Abour, Kalubia, 12511
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-2098.215460

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Objectives The aim of this study was to evaluate the corneal biomechanical properties using the ocular response analyzer(ORA) in type2 diabetic patients. Background The ORA isadevice developed in recent years and reveals the biomechanical properties of the cornea. It reflects certain biomechanical properties of the cornea, such as corneal hysteresis and corneal resistance factor. Patients and methods A total of150eyes of 75patients were enrolled in a cross-sectional prospective comparative study from May 2015 to May 2016. Patients were divided into three equal groups. ORA and HbA1c evaluation were carried out for all patients. Results The corneal hysteresis of the study groups ranged from 5.5 to 9.8mmHg for the control group (groupA), and it ranged from 6.00 to 11.4mmHg for the diabetic group(groupB), whereas it ranged from 9.5 to 15.20 in the diabetic group(groupC). The corneal resistance factor of the study groups ranged from 5.8 to 10.00mmHg for the control group(groupA), from 6.2 to 12.00mmHg for the diabetic group(groupB), and from 8.90 to 16.10mmHg for the diabetic group(groupC). The Goldmann-correlated intraocular pressure of our study groups ranged from 10 to 30mmHg for the control group(groupA), from 10 to 22mmHg for the diabetic group(groupB), and from 10.5 to 26.00mmHg for the diabetic group(groupC). The corneal-compensated intraocular pressure of the study groups ranged from 10.8 to 25mmHg for the control group(groupA), from 11.2 to 30mmHg for the diabetic group(groupB), and from 10.00 to 28.00mmHg for the diabetic group(groupC). Conclusion The corneal biomechanics in diabetic groups are significantly higher than those in the control group.


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